Sensitive troponin improves early detection of AMI

Newer sensitive troponin assays (detecting 0.04 ng/ml troponin I) showed better senstivity at detecting acute myocardial infarction at 0 amp; 3 hours compared with standard assays. Specificity was however slightly lower than standard assays, suggesting non-AMI pathologies that produce a degree of cardiomyocyte injury will also be detected. Senstivity and specificity for AMI at baseline were both around 90%. Troponin I 0.04 ng/ml was an independent risk factor for adverse events at 30 days.br /br /a href=”http://content.nejm.org/cgi/content/short/361/9/868″http://content.nejm.org/cgi/content/short/361/9/868/a