A review article on bronchiolitis reminds us that there is little evidence to support any specific therapies. Bronchodilators, steroids, adrenaline (epinephrine), CPAP, heliox, mucolytics and leukotriene antagonists are all reviewed. Of these, inhaled 3% saline as a mucolytic has some promise in that studies show it to reduce length of stay in admitted patients by one day. CPAP has been shown to reduce pCO2 but evidence of further benefit may have been limited by a lack of adequately powered studies.
Current Therapies in Bronchiolitis
Pediatr Emerg Care. 2010 Apr;26(4):302-7