Hyperglycaemia & mortality in sepsis – lactate dependent?
I like this paper for introducing a new concept to me. For years the critical care community has recognised the […]
Acute Med, All Updates, ICU, Resus
sepsis
Acute Med, All Updates, ICU, Kids, Resus
Etomidate & sepsis
A meta-analysis attempts to quantify etomidate’s effect on mortality and adrenal suppression. Of course, we all know a meta-analysis can […]
Acute Med, All Updates, ICU
Infectious biomarkers in the critically ill
A study examining patterns of procalcitonin in a group of critically ill patients(1) showed some interesting findings: Shock was associated […]
Acute Med, All Updates, ICU, Resus
More on the meaning of lactate values
A newly published study(1) reminds us that we need to do better than just identify a raised lactate in patients […]
Acute Med, All Updates, ICU, Resus
The opposite of acute kidney injury?
Prescribing in the critically ill patient can be a challenge due to a number of factors impacting on pharmacology: variable […]
Acute Med, All Updates, ICU, Resus, Ultrasound
Is diastolic worse than systolic dysfunction in sepsis?
Septic myocardial dysfunction is a well recognised contributor to shock in sepsis but for many of us we assume this […]
Acute Med, All Updates, ICU, Resus
Vasopressin – what it does and doesn't do
The current Surviving Sepsis campaign guidelines recommend that vasopressin should not be administered as the initial vasopressor in septic shock, […]
Acute Med, All Updates, ICU, Kids, Resus
Treating sepsis – have we got it the wrong way round?
In our understanding of the pathophysiology of sepsis, we often attribute organ damage and death to the excessive host response […]
Acute Med, All Updates, ICU, Resus
AF in sepsis and risk of stroke
Atrial fibrillation can occur in the setting of severe sepsis, and often presents a therapeutic conundrum for critical care physicians, […]
Acute Med, All Updates, ICU, Resus
Xigris withdrawn
Pharmaceutical company Eli Lilly has announced the withdrawal of its severe sepsis drug activated protein C, or drotrecogin alfa (proprietary […]