Caution with intraosseous adenosine
Two cases of failed cardioversion of SVT after tibial intraosseous administration of adenosine in infants are described in this month’s […]
All Updates, Guidelines, Kids, Resus
drugs
All Updates, ICU, Resus
Steroid replacement after etomidate: no benefit
More fuel for the etomidate debate… In essence: Etomidate has been a useful induction agent for RSI for many years […]
Acute Med, All Updates, ICU
Enoxaparin in acute medical patients
A large multinational study challenges the practice of routine thromboprophylaxis for hospitalised acutely ill medical patients. Enoxaparin plus graduated compression […]
Acute Med, All Updates, ICU, Resus
Xigris withdrawn
Pharmaceutical company Eli Lilly has announced the withdrawal of its severe sepsis drug activated protein C, or drotrecogin alfa (proprietary […]
Acute Med, All Updates, ICU, PHARM, Resus
Pre-hospital hypertonic saline during ACLS
A newly published study examines pre-hospital hypertonic saline during CPR. A randomised trial compared 7.2% hypertonic saline / hydroxyethyl starch […]
Acute Med, All Updates, ICU, Resus, Trauma
Reversing new oral anticoagulants
A small study on normal volunteers examined reversal of the new oral anticoagulants, Rivaroxaban and Dabigatran. Rivaroxaban is a Factor […]
All Updates, ICU, Kids, Resus
Is there nothing ketamine can't do?
As well as the benefits of cardiovascular stability, maintenance of cerebral perfusion pressure, possibly lowering ICP and providing other neuroprotective […]
Acute Med, All Updates, ICU, Kids, Resus
Why I don't give vasopressors in sepsis
It’s become popular to use the term ‘vasopressors’ or just ‘pressors’ when noradrenaline/norepinephrine or even (in some places still) dopamine […]
Acute Med, All Updates, Guidelines, ICU, PHARM, Resus
Still no cardiac arrest survival benefit from epinephrine?
A double blind randomised controlled trial showed significantly better rates of return of spontaneous circulation and hospital admission with the […]
All Updates, ICU, Kids, Resus
Steroids for sepsis in kids
A small retrospective study suggests adrenal insufficiency is common in kids with septic shock, and that steroid administration in these […]