Extreme white cell counts
Febrile children aged three months to three years with a white cell count over 25000/mm3 and fever were compared with […]
All Updates, Kids
sepsis
All Updates, ICU, Resus
The right antibiotic in septic shock makes a massive difference
A retrospective review of appropriate vs inappropriate antimicrobial therapy was undertaken in over four thousand septic shock patients from multiple […]
Acute Med, All Updates, Guidelines, Kids
WHO Guidelines for Pandemic Influenza A(H1N1) 2009
The World Health Organisation has published updated guidelines on drug treatment of Influenza A(H1N1)2009 and other influenza viruses. Their recommendations […]
All Updates, ICU, Resus
EGDT sepsis bundle challenged
An article in American Journal of Emergency Medicine by two intensivists challenges the science behind Rivers’ early goal-directed therapy (EGDT) […]
All Updates, ICU, Resus
Bad news for etomidate from CORTICUS
In an a priori substudy of the CORTICUS multi-centre, randomised, double-blind, placebo-controlled trial of hydrocortisone in septic shock, the use […]
All Updates, Kids
Identifying sick kids is still difficult
A systematic review to identify clinical features that have value in confirming or excluding the possibility of serious infection in […]
All Updates, ICU
Procalcitonin reduced antibiotic use
In a multicentre study in France, adult patients expected to stay in the intensive care unit for more than 3 […]
Acute Med, All Updates, ICU, Resus
Lactate clearance goal in sepsis
Previous work in severe sepsis/septic shock patients has shown that a decrease in lactate concentration by at least 10% during […]
All Updates, ICU
Chlorhexidine-alcohol surgical site prep
In contrast to the situation with skin preparation for intravascular catheters, there have been no recommendations for surgical practice. A […]
All Updates, ICU, Resus
Noradrenaline vs Dopamine in Shock
Another nail in dopamine’s coffin? In a blinded randomised controlled trial in shocked patients1, there was no difference in mortality […]