Amethocaine versus EMLA
A double blind randomised trial comparing amethocaine (Ametop) with EMLA was conducted on 679 kids in a New Zealand emergency […]
All Updates, Kids
All Updates, ICU, Resus
Is cerebral oxygenation negatively affected by infusion of norepinephrine in healthy subjects?
An interesting study on nine healthy volunteers demonstrated noradrenaline infusions to increase MAP without increasing cardiac output (by increasing systemic […]
Acute Med, All Updates, ICU, Resus
Which COPD patients should be admitted to the ICU?
A multicenter ICNARC-supported study of 832 COPD patients admitted to intensive care units showed a 180-day mortality of 37.9%. A […]
All Updates, ICU, Resus
A Systematic Review of Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults
This thorough review confirms that steroids have no clear benefit on mortality in severe sepsis / septic shock. Looking at […]
All Updates, PHARM, Resus
Etomidate versus ketamine for rapid sequence intubation
Finally a well designed blinded randomised controlled trial on this subject. 0.3 mg/kg etomidate was compared with 2mg/kg ketamine for […]
All Updates, PHARM
Ambulance transport induces stress
Plasma levels of adrenaline and noradrenaline increased signficantly in patients with acute coronary syndrome during ambulance transportation – a finding […]
Kids, PHARM, Resus, Trauma
Ketamine lowered ICP in brain-injured kids
Ketamine lowered ICP in brain-injured kids Ventilated children between the ages of 1 and 16 with traumatic brain injury and […]
Acute Med, Resus
Guidelines for D.I.C.
2009 Guideline for the Diagnosis and Managment of Disseminated Inravascular Coagulation DIC guideline available here Other useful guidelines from the […]
Acute Med, Resus
NINDS does not support 'time-is-brain' when re-presented
The first ‘positive’ trial that really started it all for stroke thrombolysis has been re-presented by showing that the change […]
Acute Med
CRP improves mortality prediction by prognostic scales in community-acquired pneumonia
In admitted patients with community acquired pneumonia, adding CRP to either the CURB-65 score or pneumonia severity index improved the […]