Lactate clearance goal in sepsis
Previous work in severe sepsis/septic shock patients has shown that a decrease in lactate concentration by at least 10% during […]
Acute Med, All Updates, ICU, Resus
shock
All Updates, ICU, Resus
Noradrenaline vs Dopamine in Shock
Another nail in dopamine’s coffin? In a blinded randomised controlled trial in shocked patients1, there was no difference in mortality […]
All Updates, ICU, Resus
Effect on noradrenaline on tissue oxygen delivery
Some persist in thinking and teaching that the ‘vasopressor’ noradrenaline (norepinephrine) increases mean arterial pressure (MAP) simply by increasing systemic […]
All Updates, ICU, Resus
End expiratory occlusion
OBJECTIVE: During mechanical ventilation, inspiration cyclically decreases the left cardiac preload. Thus, an end-expiratory occlusion may prevent the cyclic impediment […]