Tag Archives: procedures

Newborn mask ventilation

Seventy doctors and nurses from neonatal units administered positive pressure ventilation to a term newborn manikin using a Neopuff T-piece device. Recordings were made (1) before training, (2) after training in mask handling and (3) 3 weeks later. Leak and obstruction were calculated.
Median (IQR) leak was 71% (32–95%) before training, 10% (5–37%) directly after training and 15% (4–33%) 3 weeks later (p<0.001). When leak was minimal, gas flow obstruction was observed before, directly after training and 3 weeks later in 46%, 42% and 37% of inflations, respectively.
The training provided included the following demonstrated mask technique:

  1. Place the manikin’s head in a neutral position and gently roll the mask upwards onto the face from the tip of the chin.
  2. Hold the mask with the two-point-top hold where the thumb and index finger apply balanced pressure to the top flat portion of the mask where the silicone is thickest.
  3. The stem is not held and the fingers should not encroach onto the skirt of the mask.
  4. The thumb and index finger apply an even pressure on top of the mask.
  5. The third, fourth and fifth fingers perform a chin lift with the same pressure upwards as applied by the thumb and index finger downwards.


In this technique the mask is squeezed onto the face, between the downward thrust of the fingers and upward pull of the chin lift.
Leak and obstruction with mask ventilation during simulated neonatal resuscitation
Arch Dis Child Fetal Neonatal Ed 2010;95:F398-F402
Even with the right technique, adequacy of ventilation can be hard to assess. Principles to bear in mind are:

  • International guidelines recommend that infants with inadequate breathing or bradycardia be given positive pressure ventilation (PPV) via a face mask with a self-inflating bag, flow-inflating bag or T-piece device.
  • Adequacy of ventilation is then judged by assessing the heart rate.
  • However, if the heart rate does not increase, chest wall movements should be assessed to gauge adequacy of ventilation.
  • A human observational study reported a mean VT of 6.5 ml/kg in spontaneous breathing preterm infants in the first minutes of life.
  • When assisted ventilation is required, a peak inflating pressure (PIP) is chosen with the assumption that this will deliver an appropriate VT.
  • However, lung compliance and therefore the PIP required to deliver an appropriate VT vary in the minutes after birth.
  • It is likely that there are even greater differences between infants as the mechanical properties of the lung vary with gestational age and disease states.
  • In addition, many infants breathe during PPV adding to the inconsistency of VT delivered with a set PIP. Therefore, relying on a fixed PIP and subjective assessment of chest wall movement may result in either under- or over-ventilation.
  • Animal studies have shown that PPV with VT >8 ml/kg or inflations with large VTs can damage the lungs.

In an observational study of actual newborn resuscitations in Melbourne, researchers measured inflating pressures and VT delivered using a respiratory function monitor, and calculated face mask leak. After 60 seconds of PPV, resuscitators were asked to estimate VT and face mask leak. These estimates were compared with measurements taken during the previous 30 s.
In 20 infants, the median (IQR) expired tidal volume (VTe) delivered was 8.7 ml/kg (5.3–11.3). VTe and mask leak varied widely during each resuscitation and between resuscitators, who were also poor at estimating VT and mask leak.
Assessment of tidal volume and gas leak during mask ventilation of preterm infants in the delivery room.
Arch Dis Child Fetal Neonatal Ed. 2010 Nov;95(6):F393-7

Tracheobronchial Foreign Bodies in Children

Asphyxiation by an inhaled foreign body is a leading cause of accidental death among children younger than 4 years. A review article examining 12,979 paediatric bronchoscopies made the following observations:
Epidemiology

  • Most aspirated foreign bodies are organic materials (81%, confidence interval [CI] = 77%-86%), nuts and seeds being the most common.
  • The majority of foreign bodies (88%, CI = 85%-91%) lodge in the bronchial tree, with the remainder catching in the larynx or trachea.
  • The incidence of right-sided foreign bodies (52%, CI = 48%-55%) is higher than that of left-sided foreign bodies (33%, CI = 30%-37%). A small number of objects fragment and lodge in different parts of the airways.
  • A history of a witnessed choking event is highly suggestive of an acute aspiration.
  • A history of cough is highly sensitive for foreign body aspiration but is not very specific. On the other hand, a history of cyanosis or stridor is very specific for foreign body aspiration but is not very sensitive.
  • Signs and symptoms typical in delayed presentations include unilateral decreased breath sounds and rhonchi, persistent cough or wheezing, recurrent or nonresolving pneumonia, or rarely, pneumothorax.
  • Only 11% (CI = 8%-16%) of the foreign bodies were radio-opaque on radiograph, with chest radiographs being normal in 17% of children (CI = 13%-22%).
  • The common radiographic abnormalities included localized emphysema and air trapping, atelectasis, infiltrate, and mediastinal shift.
  • Although rigid bronchoscopy is the traditional diagnostic “gold standard,” the use of computerized tomography, virtual bronchoscopy, and flexible bronchoscopy is increasing.
  • Reported mortality during bronchoscopy is 0.42%.
  • Although asphyxia at presentation or initial emergency bronchoscopy causes some deaths, hypoxic cardiac arrest during retrieval of the object, bronchial rupture, and unspecified intraoperative complications in previously stable patients constitute the majority of in-hospital fatalities.
  • Major complications include severe laryngeal edema or bronchospasm requiring tracheotomy or reintubation, pneumothorax, pneumomediastinum, cardiac arrest, tracheal or bronchial laceration, and hypoxic brain damage (0.96%).
  • Aspiration of gastric contents is not reported.

End expiratory film: delayed emptying of the left lung suggests local air trapping

Anaesthetic considerations

  • Preoperative assessment should determine where the aspirated foreign body has lodged, what was aspirated, and when the aspiration occurred (“what, where, when”).
  • The choices of inhaled or IV induction, spontaneous or controlled ventilation, and inhaled or IV maintenance may be individualized to the circumstances. Although several anesthetic techniques are effective for managing children with foreign body aspiration, there is no consensus from the literature as to which technique is optimal.
  • An induction that maintains spontaneous ventilation is commonly practiced to minimize the risk of converting a partial proximal obstruction to a complete obstruction.
  • Controlled ventilation combined with IV drugs and paralysis allows for suitable rigid bronchoscopy conditions and a consistent level of anesthesia.
  • Close communication between the anesthesiologist, bronchoscopist, and assistants is essential.

The Anesthetic Considerations of Tracheobronchial Foreign Bodies in Children: A Literature Review of 12,979 Cases
Anesth Analg. 2010 Oct;111(4):1016-25

Expert not happy with cricoid

Evidence-based medicine reminds us to beware ‘experts’. However, here’s one self-described expert who talks some sense. Doctor (Doktor?) HJ Priebe from the University Hospital Freiburg in Germany suggests the risk of harm outweighs the risk of benefit from this procedure:
Despite the lack of evidence for its effectiveness and evidence for numerous deleterious effects, cricoid pressure is still considered a standard of care during rapid sequence induction, and its application is considered mandatory in patients at high risk for gastric regurgitation. However, by using cricoid pressure, we may well be endangering more lives by causing airway problems than we are saving in the hope of preventing pulmonary aspiration. It is dangerous to consider cricoid pressure to be an effective and reliable measure in reducing the risk of pulmonary aspiration and to become complacent about the many factors that contribute to regurgitation and aspiration. Cricoid pressure is not a substitute for optimal patient preparation. Ensuring optimal positioning and a rapid onset of anesthesia and muscle relaxation to decrease the risk of coughing, straining or retching during the induction of anesthesia are likely more important in the prevention of pulmonary aspiration than cricoid pressure.

‘At the time of Sellick’s description of the technique of cricoid pressure, morbidity and mortality from pulmonary aspiration during the induction of anesthesia in the surgical population in general, and the obstetric population in particular, were of great concern. At that time, the concept of cricoid pressure was highly attractive. However, during the past 48 years, many aspects of anesthetic management have considerably changed, and knowledge has advanced. By today’s standards, cricoid pressure can no longer be considered an evidence-based practice. This is why more and more anesthetists (including myself) no longer apply cricoid pressure.

Vielen Dank, Herr Doktor!
Cricoid pressure: an expert’s opinion
Minerva Anestesiol 2009;75:710-4 – Full text
Just as well really, because these guys show many people don’t know how to do it anyway! Cases were identified in which pressure was mistakenly applied to the thyroid cartilage and even the sternocleidomastoid muscles!
Variable application and misapplication of cricoid pressure
J Trauma. 2010 Nov;69(5):1182-4

Negative laparotomy

The complication rate after a negative or nontherapeutic laparotomy is reported to be substantial but most of this reported morbidity is because of associated injuries and is not related to the abdominal exploration. On the other hand, the morbidity and mortality associated with a delay in taking the injured patient to the operating room is well recognised. A retrospective study attempts to show that when injury severity (using TRISS) is controlled for, negative laparotomy did not significantly increase the complication burden compared with no laparotomy in blunt abdominal trauma patients.

“Never Be Wrong”: The Morbidity of Negative and Delayed Laparotomies After Blunt Trauma
J Trauma. 2010 Dec;69(6):1386-92

The four-stage approach to teaching skills

Instructors and graduates of certain Life Support courses will be familiar with the ‘four stage’ approach to teaching procedural skills (demonstration, deconstruction, formulation, performance):

  1. Silent run through in which teacher performs without commentary;
  2. teacher then performs while commentating;
  3. teacher then performs with commentary from student(s);
  4. finally student performs and commentates.

Two randomised studies published this month showed no improvement in skills performance with this teaching method compared with simpler approaches. One involved needle cricothyroidotomy1 and another laryngeal mask insertion2.
An accompanying editorial3 acknowledges that this might put an end to this educational dogma, but one should consider that the procedures taught in these studies were simple to perform, and the results might not be extendable to more complex procedures.
The editorial points out there are some interesting data describing the neurophysiological basis of learning. Observing actions made by others activates the cortical circuits responsible for the planning and execution of those same actions; this visual-motor coupling happens through a neuronal matching network called the Mirror Neuron System (MNS). Listening to a verbal description of a skill can activate the same visual-motor circuit as those activated by the hand or the leg when completing the skill. Even during new motor pattern formation there is significant NMS activation, supporting the concept that the building of motor memories is based on the combination of observation and execution.
The ingredients of the complex mechanism of motor learning are observation, listening and immediate execution. The priority that should be given to each of the individual components of motor skills teaching is difficult to quantify and should be the subject of future research.
The editorialists conclude: The four-stage approach has been used for years with no evidence of better skill acquisition and retention compared with traditional methods. Medical educators need high-quality data to address the knowledge gaps for this topic and the two studies in this issue have set a precedent for future research. In our opinion, we should continue to use the four-stage approach to skill teaching while waiting for more evidence of a superior approach.
I differ slightly in my conclusion: if I have a limited time to teach a skill station (like airway management in the APLS course), I know I’m a little more justified in ditching this time consuming ritual in favour of more hands-on time for the paying delegates.
1. Emergency skill training—A randomized controlled study on the effectiveness of the 4-stage approach compared to traditional clinical teaching
Resuscitation. 2010 Dec;81(12):1692-7
2. A randomised trial comparing a 4-stage to 2-stage teaching technique for laryngeal mask insertion
Resuscitation. 2010 Dec;81(12):1687-91
3. The four-stage approach to teaching skills: The end of a dogma?
Resuscitation. 2010 Dec;81(12):1607-8
Neurologist Vilayanur Ramachandran explains the mirror neuron system in this video from TED.com:

Needle crike: low rate and allow exhalation

Two dedicated devices for transtracheal oxygen delivery through a cricothyroidotomy needle are available, the ENK Oxygen Flow Modulator (ENK) and the Manujet. Both maintain oxygenation, but the ENK is thought to achieve better ventilation (as previously shown in a pig model) because of a continuous flow that provides CO2 washout between insufflations. Very little is known concerning the lung pressures generated with these 2 devices, so a study using a simulated trachea and artificial lung model sought to determine oxygen flow, tidal volumes, and airway pressures at different occlusion rates and during both simulated partial and complete upper airway obstruction.

Manujet

Gas flow and tidal volume were 3 times greater with the Manujet than the ENK (approximately 37 vs 14 L/min and 700 vs 250 mL, respectively) and were not dependent on the respiratory rate. In the absence of ventilation, the ENK delivered a 0.6+/-0.1 L/min constant gas flow. In the totally occluded airway, lung pressures increased to 136 cm H2O after 3 insufflations with the Manujet, whereas the ENK, which has a pressure release vent, generated acceptable pressures at a low respiratory rate (4 breaths/min) (peak pressure at 27.7 +/-0.7 and end-expiratory pressure at 18.8+/- 3.8 cm H2O). When used at a respiratory rate of 12 breaths/min, the ENK generated higher pressures (peak pressure at 95.9 +/- 21.2 and end-expiratory pressure at 51.4+/- 21.4 cm H2O). In the partially occluded airway, lung pressures were significantly greater with the Manujet compared with the ENK, and pressures increased with the respiratory rate with both devices. Finally, the gas flow and tidal volume generated by the Manujet varied proportionally with the driving pressure.
The authors asset that this study confirms:

  • the absolute necessity of allowing gas exhalation between 2 insufflations and
  • maintaining low respiratory rates during transtracheal oxygenation.

In the case of total airway obstruction, the ENK may be less deleterious because it has a pressure release vent. Using a Manujet at lower driving pressures may decrease the risk of barotrauma and allow the safe use of higher respiratory rates

ENK

Oxygen delivery during transtracheal oxygenation: a comparison of two manual devices
Anesth Analg. 2010 Oct;111(4):922-4

Pre-hospital amputation

British trauma surgeon and pre-hospital pioneer Professor Keith Porter describes how to do a pre-hospital amputation in this months EMJ. Thankfully the procedure is only rarely necessary and often only requires cutting remaining skin bridges with scissors. The indications are:

  • An immediate and real risk to the patient’s life due to a scene safety emergency
  • A deteriorating patient physically trapped by a limb when they will almost certainly die during the time taken to secure extrication
  • A completely mutilated non-survivable limb retaining minimal attachment, which is delaying extrication and evacuation from the scene in a non-immediate life-threatening situation
  • The patient is dead and their limbs are blocking access to potentially live casualties

simple equipment for amputation

The recommended procedure is:

  1. Ketamine anaesthesia
  2. Apply an effective proximal tourniquet
  3. Amputate as distally as possible
  4. Perform a guillotine amputation
  5. Apply haemostats to large blood vessels
  6. Leave the tourniquet in situ
  7. Apply a padded dressing and transport to hospital

Remember: the requirement for prehospital amputation other than cutting minimal soft tissue bridges is rare. However pre-hospital critical care physicians should be trained and equipped to amputate limbs in order to save life. Probably good to have a Gigli saw in your pack and to familiarise yourself with its use, as shown here:

Sydney HEMS doctors training in amputation

Prehospital amputation
Emerg Med J 2010 27: 940-942

Propofol for kids in the ED

A systematic review of the use of propofol for paediatric procedural sedation (PPS) identified sixty studies and 17 066 published paediatric propofol sedations performed outside the operating theatre setting. The incidence of complications were: desaturation 9.3%, apnoea 1.9%, assisted ventilation 1.4%, hypotension 15.4%, unplanned intubation 0.02%, emesis post procedure 0.14%, laryngospasm 0.1% and bradycardia 0.1%. There are many confounding variables that influence the likelihood of these events: adjunct opiates, propofol dosing strategies and supplemental oxygen. These rates of minor adverse events are similar to that published for ED sedation with other sedation agents

There were no reported incidents of aspiration or emesis during sedation and there were no deaths associated with procedural propofol sedation. The authors conclude: “the published adverse event data for paediatric propofol sedation support its ongoing use in the ED for appropriately selected paediatric patients by experienced physicians who are able to provide advanced cardiorespiratory support.
Review article: Safety profile of propofol for paediatric procedural sedation in the emergency department
Emerg Med Australas. 2010 Aug;22(4):265-86

Left molar approach

The left molar approach is a technique to improve the view at laryngoscopy using a standard macintosh laryngoscope. It was described by Yamamoto1 as follows:

  • insert the blade from the left corner of the mouth at a point above the left molars;
  • the tip of the blade is directed posteromedially along the groove between the tongue and the tonsil until the epiglottis and glottis come into sight;
  • before elevating the epiglottis, the tip of the blade is kept in the midline of the vallecula and the blade is kept above the left molars;
  • the view provided is framed by the flange, the lingual surface of the blade, and the tongue bulged to right of the blade.


The success of this approach in comparison with alternatives has been reproduced by others2. However although Yamamoto and others demonstrated that this improved the laryngoscopic view, actual intubation may still be difficult because of the limited access to the cords, in part caused by the bulging of the tongue.
Physicians from Turkey described a case3 of an unpredicted difficult airway to demonstrate that the use of the gum elastic bougie can facilitate intubation which had otherwise not been successful via the left molar approach.
The take home message for me is that if I have a grade IV view despite my usual first-pass success optimisation manoeuvres such as positioning, reducing or releasing cricoid pressure, and providing external laryngeal manipulation, it is worth trying the left molar approach in combination with a bougie to gain a view of the glottis and to pass the tube.
1. Left-molar Approach Improves the Laryngeal View in Patients with Difficult Laryngoscopy
Anesthesiology. 2000 Jan;92(1):70-4 Full Text
2. Comparative Study Of Molar Approaches Of Laryngoscopy Using Macintosh Versus Flexitip Blade
The Internet Journal of Anesthesiology 2007 : Volume 12 Number 1
3. The use of the left-molar approach for direct laryngoscopy combined with a gum-elastic bougie
European Journal of Emergency Medicine December 2010 ;17(6):355-356

LMA not always successful; needle crike fails often

A meta-analysis of pre-hospital airway control techniques evaluated alternative techniques to tracheal intubation. The outcome was placement success; there were no data on effectiveness of ventilation or other clinical outcomes. Although limited by poor quality studies, there are some interesting findings.
The pooled placement success rates for Combitube and LMA, were similar but unimpressive, with nonphysician placement success rates of 83.0% and 82.7%, respectively. The authors point out that while these devices might offer potential advantages over conventional tracheal intubation in terms of reduced training requirements, or perhaps fewer or less severe complications, they should not be expected to provide higher airway management success rates than conventional tracheal intubation.

Low success rates for this 'rescue procedure'. Just get your scalpel...

They identified only four studies reporting the success rates of needle cricothyroidotomy (NC). Regardless of patient circumstances or clinician credentials, the NC success rate was ubiquitously low, ranging from 25.0% to 76.9%. The pooled results for the 18 surgical cricothyroidotomy (SC) studies produced substantially higher success rates, although the success rate for all nonphysician clinicians was still only 90.4%. The authors state: “EMS systems that choose to incorporate a percutaneous airway procedure into their airway management protocols should recognize that the success rate of SC far exceeds that of NC”.
A meta-analysis of prehospital airway control techniques part II: alternative airway devices and cricothyrotomy success rates
Prehosp Emerg Care. 2010 Oct-Dec;14(4):515-30