Category Archives: All Updates

Do all comatose patients need intubation?

In non-trauma patients, do you base your decision to intubate patients with decreased conscious level on the GCS? These guys in Scotland describe a series of poisoned patients with GCS range 3-14 managed on an ED observation unit without tracheal intubation, with no demonstrated cases of aspiration. They say: ‘This study suggests that it can be safe to observe poisoned patients with decreased consciousness, even if they have a GCS of 8 or less, in the ED‘. Small numbers, but gets you thinking. This subject would make a great randomised controlled trial.
Decreased Glasgow Coma Scale score does not mandate endotracheal intubation in the emergency department
J Emerg Med. 2009 Nov;37(4):451-5

Is defibrillation an electric threat for bystanders?

No rescuer or bystander has ever been seriously harmed by receiving an inadvertent shock while in direct or indirect contact with a patient during defibrillation. New evidence suggests that it might even be electrically safe for the rescuer to continue chest compressions during defibrillation if self-adhesive defibrillation electrodes are used and examination gloves are worn. This paper reviews the existing evidence, but warns more definite data are needed to make absolutely sure that there is no risk before defibrillation safety recommendations are changed.

Is external defibrillation an electric threat for bystanders?
Resuscitation. 2009 Apr;80(4):395-401

Oblique view for IJV cannulation

Simple really. Using the transverse view the needle tip can be hard to visualise. In the longitudinal view you don’t see the carotid artery. Applying an oblique view with an obliquely oriented needle “uses the superiority of the short axis view by visualizing all of the important surrounding structures (artery and vein) in an oblong view while allowing continuous real-time visualization of the long axis of the needle, therefore providing a larger, more easily visible target with a brighter more easily recognized needle.” The ultrasound probe is orientated at approximately 45° so that the medial end of the ultrasound probe aligns with the patient’s contralateral nipple or shoulder.

The oblique view: an alternative approach for ultrasound-guided central line placement
J Emerg Med. 2009 Nov;37(4):403-8
Full Text Article

10 ml syringe for Valsalva manoeuvre

Previous studies have suggested the following are necessary for a successful Valsalva manoeuvre with maximum vagal effect:

  • Supine posturing
  • Duration of 15 seconds
  • Pressure of 40 mmHg (with an open glottis)

One popular method of generating a Valsalva Manoeuvre is to get the patient to blow into a syringe in an attempt to move the plunger. Different syringe sizes were tested. A 10ml (Terumo) syringe was best
The 10 mL syringe is useful in generating the recommended standard of 40 mmHg intrathoracic pressure for the Valsalva manoeuvre
Emerg Med Australas. 2009 Dec;21(6):449-54

Stopping infusions before PCI transfer

An interhospital transport service introduced a no infusions policy for patients being transferred for primary coronary intervention, instead giving a bolus of heparin and glycoprotein 2b-3a inhibitor prior to transfer, along with non-intravenous nitrates (if needed). Discontinuing infusions during transport resulted in a significant reduction in transport times with no adverse effect on hospital length of stay or mortality. It did not significantly extend the time the patient spent in the catheterisation laboratory, nor did it impact the incidence of TIMI III flow. It did not impact the incidence of readmission to the hospital for cardiac-related chief complaints.
Transporting without infusions: effect on door-to-needle time for acute coronary syndrome patients
Prehosp Emerg Care. 2010 Apr 6;14(2):159-63

Better TBI outcome with HEMS

A retrospective study from Italy compared outcomes of head injured patients cared for by a ground ambulance service (GROUND) with those managed by a HEMS team that included an experienced pre-hospital anaesthetist. Interestingly 73% of the ground group were also attended by a physician, but one ‘with only basic life-support capabilities and no formal training in airways management’. Despite these limited skills a results table shows that 36% of the GROUND group were intubated on scene (compared with 92% of the HEMS group), although without the use of neuromuscular blockers.

The HEMS group consisted of 89 patients and the GROUND group of 105 patients. There were no statistical differences in age, ISS, aISShead, or GCS, although arterial hypotension at arrival at the ER was present in 18% of HEMS patients and in 36% of GROUND patients (P < 0.001).
The overall mortality rate was lower in the HEMS than in the GROUND group (21 vs. 25% , P < 0.05). The survival with or without only minor neurological disabilities was higher in the HEMS than in the GROUND group (54 vs. 44% respectively, P < 0.05); among the survivors, the rate of severe neurological disabilities was lower in the HEMS than in the GROUND group (25 vs. 31%, P < 0.05). The out-of-hospital phase duration was longer in the HEMS group but this group had a faster time to definitive care (neurosurgery or neurocritical care).
Influence of prehospital treatment on the outcome of patients with severe blunt traumatic brain injury: a single-centre study
Eur J Emerg Med. 2009 Dec;16(6):312-7

Abnormal head CT in altered mental status

In a study of 674 patients with altered mental status who received a CT scan of the brain, logistic regression analysis identified a series of clinical factors that were associated with an abnormal CT result.
Factors with an adjusted odds ratio between 1 and 2.5 included GCS less than 15, focal weakness, diastolic blood pressure greater than 80mmHg and antiplatelet use.
Four variables were associated with an adjusted odds ratio of 2.5 or above. These included presence of headache, dilated pupils (either unilateral or bilateral), upgoing plantar response and anticoagulant use.
Identifying risk factors for an abnormal computed tomographic scan of the head among patients with altered mental status in the Emergency Department
Eur J Emerg Med. 2009 Sep 21. [Epub ahead of print]

EGDT sepsis bundle challenged

An article in American Journal of Emergency Medicine by two intensivists challenges the science behind Rivers’ early goal-directed therapy (EGDT) protocol for severe sepsis / septic shock. In a nutshell:

  • Rivers’ study was small (n = 263), nonblinded, industry-supported and single-center
  • early fluids and antibiotics are a sound idea, but other components of EGDT are flawed
  • targeting a CVP is meaningless and could result in hypovolaemia or pulmonary oedema; dynamic markers of preload responsiveness such as pulse pressure variation or IVC diameter variation are better guides to fluid resuscitation
  • ScvO2 may be normal or elevated in septic shock patients; the low average ScvO2 in Rivers’ study has not been reproduced in subsequent studies.
  • packed cells have significant side effects and their non-deformability, pro-inflammatory and pro-thrombotic effects may impair microvascular perfusion and paradoxically worsen tissue oxygen delivery
  • dobutamine can potentially further worsen the haemodynamic status of patients with hypovolaemia, vasodilation, or a hyperdynamic circulation, which cannot be differentiated using CVP and ScvO2

Early goal-directed therapy: on terminal life support?
Am J Emerg Med. 2010 Feb;28(2):243-5
I like this paper, mainly because I have been uncomfortable with the chasing of arbitrary targets for some time. My own practice is to try to improve markers of organ hypoperfusion (such as lactate, urine output, mental status, and skin perfusion as well as blood pressure) by early antibiotics, fluid resuscitation guided by clinical and sonographic (IVC) signs, and vasoactive drugs guided by clinical and sonographic (basic echo) findings. I place a central venous catheter for access for the vasoactive drugs, rather than to get a CVP reading. I do measure ScvO2 with a central venous blood gas, but have rarely seen one below 70% even in severely shocked patients – I’m far more interested in clearing the lactate, as are these guys.

Biphasic shocks for AF and Atrial flutter

Based on a study of 453 consecutive patients undergoing their first transthoracic electrical cardioversion for atrial tachyarrhythmias, recommendations were developed to aim at delivering the lowest possible total cumulative energy with ≤2 consecutive shocks using the specific truncated exponential biphasic waveform incorporated in Medtronic Physio-Control devices: they recommend an initial energy setting of 50 J in patients with atrial flutter or atrial tachycardia, of 100 J in patients with atrial fibrillation (AF) of 2 or less days in duration, and of 150 J with AF of more than 2 days in duration. If the initial shock fails to restore sinus rhythm, a rescue shock of 250 J for AFL/AT or of 360 J for AF should be applied to secure the highest possible probability of successful cardioversion for each patient.
Optimization of initial energy for cardioversion of atrial tachyarrhythmias with biphasic shocks
Am J Emerg Med. 2010 Feb;28(2):159-65